The heart protection study: statins for all those at risk?
نویسندگان
چکیده
منابع مشابه
Heart failure: statins for all?
Although there is increasing evidence of benefit in using statins to treat patients with non-ischaemic heart failure, it is not yet possible to recommend the routine use of these drugs in all heart failure patients, irrespective of the aetiology. T he endothelium is an essential structural and functional element of the cardiovascular system and constitutes the largest endocrine system in the or...
متن کاملThe Heart Protection Study: high-risk patients benefit from statins, regardless of LDL-C level.
The landmark Heart Protection Study (Lancet 2002; 360:7-22) found benefit in treating subjects at high risk of a coronary event with simvastatin 40 mg daily, regardless of baseline low-density lipoprotein cholesterol level and in all subgroups, including women and the elderly. The study found no benefit of simvastatin therapy in preventing noncardiac events (eg, dementia, osteoporotic fractures...
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Statins for people at low risk.
Statins are the UK’s most commonly prescribed drugs and are among the most widely prescribed drugs globally. Though their use in people at high risk of stroke and heart disease is uncontroversial, recent recommendations to treat much larger numbers of people at low risk 3 have caused a storm of controversy. Most hotly debated are the nature and frequency of side effects of statins and whether a...
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The study by Frolich et al1 in this issue of Circulation adds to the body of evidence that statins as a class of drugs have effects that reduce the chance of cancer initiation and progression, recapitulating findings showing reductions in cancer-related mortality in statin users in other major malignancies such as breast and prostate cancer.2,3 The authors are explicit in recognizing the flaws ...
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ژورنال
عنوان ژورنال: Journal of Clinical Pharmacy and Therapeutics
سال: 2002
ISSN: 0269-4727,1365-2710
DOI: 10.1046/j.1365-2710.2002.00403.x